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Brief Interventions Outside Substance Abuse Treatment SettingsBrief interventions are commonly administered in nonsubstance abuse treatment settings, often referred to as opportunistic settings, where clients are not seeking help for a substance abuse disorder but have come to receive medical treatment, to meet with an EAP counselor, or to respond to a court summons (see Figure 2-10 for a list of health care and other professionals who often conduct brief substance use interventions). These settings and many others provide a multitude of opportunities to help people change their substance abuse patterns. It is unrealistic and unnecessary for providers in opportunistic settings to avoid working with people with a range of substance abuse problems including substance abuse disorders and merely to refer them for specialty care (Miller et al., 1994). Many clients do not use alcohol, for example, at a level that requires specialized treatment. Others who use at moderate or severe levels may be unwilling or unable to participate in specialized, mainstream substance abuse treatment programs. Moreover, some individuals may attach a stigma to attending treatment versus general health care services. Older adults and women often do not seek or engage in treatment because of stigma. An individual's level of substance use is detected through screening instruments, medical tests (e.g., urine testing), observation, or simply asking about consumption patterns. Those considered to have risky or excessive patterns of substance abuse or related problems can receive a brief intervention that rarely requires more than several sessions, each lasting only 5 minutes to 1 hour (average = 15 minutes). The goal of a brief intervention is to raise the recipient's awareness of the association between the expressed problem and substance abuse and to recommend change, either by natural, client-directed means or by seeking additional substance abuse treatment. Because the recipient usually does not expect to have a substance abuse problem identified, he may or may not be motivated to apply any recommendations. The brief intervention is highly structured and focuses on delivering a message about the individual's substance abuse and advice to reduce or stop it. If the initial intervention does not result in substantial improvement, the professional may refer the individual for additional specialized substance abuse treatment. Treatment providers who work in settings other than substance abuse treatment must be flexible when assessing, planning, and carrying out brief interventions. For example, they will likely encounter more risky drinkers than alcohol-dependent individuals (in the United States there are four times as many risky drinkers as dependent drinkers [Mangione et al., 1999]). Some research indicates that the potential for brief interventions to reduce the harm, problems, and costs associated with moderate to heavy alcohol use by risky drinkers significantly surpasses the effectiveness from applications of brief interventions on substance-dependent individuals (Higgins-Biddle et al., 1997). Other research on brief interventions, as presented below, highlights some of the more rigorous studies with positive outcomes. The costs of alcohol abuse to society, as interpreted by health care costs, lost productivity, and criminal activity, are enormous, and brief interventions are a cost-effective technique to address such abuse. Typically these brief interventions act as an early intervention before or close to the development of alcohol-related problems and primarily entail instructional and motivational components addressing drinking behavior. In substance abuse treatment, brief interventions are used to assist in the treatment engagement process and to deal with specific individual, family, or treatment-related issues. When delivering a brief intervention in any treatment setting, the provider should be mindful of room conditions and interruptions because client confidentiality is of utmost importance. Federal law requires that chart notes or other records on substance abuse be kept apart from the rest of the client's main chart. For example, if a medical client in a primary care clinic is also seen by an alcohol and drug counselor for treatment of a substance abuse disorder, those medical records are strictly protected by Federal law and may not be put in the client's chart. (For more information on these Federal laws, see TIP 24, A Guide to Substance Abuse Services for Primary Care Clinicians [CSAT, 1997].) Heather makes an important distinction between brief interventions that are delivered in opportunistic settings where patients are not directly seeking help for a substance abuse disorder and those conducted in treatment environments where patients are seeking the help of specialists (Heather, 1995). Brief interventions conducted in opportunistic settings tend to be shorter, rely less on theory and more on an existing clinician-client relationship, and are less expensive because they are offered as part of an existing service. Conducting Brief Interventions With Older AdultsOlder adults present unique challenges in applying brief intervention strategies for reducing alcohol consumption. The level of drinking necessary to be considered risky behavior is lower than for younger individuals (Chermack et al., 1996). Intervention strategies should be nonconfrontational and supportive due to increased shame and guilt experienced by many older problem drinkers. As a result, older adult problem drinkers find it particularly difficult to identify their own risky drinking. In addition, chronic medical conditions may make it more difficult for clinicians to recognize the role of alcohol in decreased functioning and quality of life. These issues present barriers to conducting effective brief interventions for this vulnerable population. For more on this topic, refer to TIP 26, Substance Abuse Among Older Adults (CSAT, 1998b). Research FindingsBrief interventions for substance abuse have been implemented since the 1960s. The literature in this area includes theoretical articles, clinical case studies and recommendations, quasi-experimental studies, and randomized controlled experimental research trials. Many of the brief intervention clinical trials have been conducted in the United States and Europe since the early 1980s, and most have focused on alcohol use. There is some experimental research on brief interventions for drug use but very little has been published to date. This is an area of ongoing and future work. Reviews of Brief Intervention StudiesA 1995 review article (Kahan et al., 1995) sorted through 43 relevant articles found in MEDLINE published from 1966 to 1985 and 112 in EMBASE published from 1972 to 1994. Another, more recent review (Wilk et al., 1997) culled nearly 6,000 articles from MEDLINE and PsychLIT searches from 1966 to 1995 to find 99 that met criteria for closer inspection. A total of 11 of the articles found by Kahan and colleagues and 12 of those reviewed by Wilk and associates had control groups, adequate sample sizes, and specified criteria for brief interventions. The most recent reviews of brief intervention studies concluded that brief interventions have merit, especially for carefully selected clients and can be applied successfully in several settings for different purposes (Bien et al., 1993; Kahan et al., 1995; Mattick and Jarvis, 1994; Wilk et al., 1997). The review by Bien and colleagues was one of the first to categorize brief interventions and evaluate their effectiveness according to the stated goals and settings in which they were conducted. After examining 12 controlled studies of strategies to improve clients' acceptance of referrals for additional specialist treatment or return to the clinic for additional treatment following an initial visit, Bien and colleagues concluded that relatively simple strategies and specific aspects of counselors' styles can increase rates of followthrough on referrals as well as improve initial engagement and participation in treatment (Bien et al., 1993). Only one unsuccessful trial of referral procedures is described, and the failure is attributed to the fact that all subjects had previously failed to respond to brief advice about getting into treatment for alcoholism. Bien and colleagues also examined 11 well-conducted trials of brief interventions for excessive drinkers identified in health care settings (including the large-scale, 10-nation World Health Organization [WHO] study) (Bien et al., 1993). They found that eight of the studies showed significant reductions in alcohol consumption levels and/or associated problems for the subjects receiving brief, drinking-focused interventions in comparison with those receiving no counseling. Three other studies found no significant differences between experimental and control groups at followup, although drinking levels and other problem measures were reduced in both groups. Bien and colleagues concluded that it is better for health care providers in opportunistic settings such as primary care to intervene in a nonjudgmental motivational format than it is to provide no intervention to patients who did not expect to have their drinking patterns evaluated. In addition, these authors also reviewed 13 randomized clinical trials comparing brief interventions to a range of more extensive therapies in specialized alcohol treatment settings and found that shorter counseling was, with remarkable consistency, comparable in impact to more traditional approaches in yielding specified outcomes (Bien et al., 1993). Only two studies reported an advantage of more extensive treatment over brief interventions on some outcome measures. They concluded that no evidence supports the inferiority of brief interventions in comparison with more extensive treatment offered by treatment specialists to patients who are seeking help for their alcohol-related problems. Heather argues, however, that the findings do not support the statement that the effectiveness of brief interventions is equal to that of other studied treatments for alcohol abuse (Heather, 1995). Finally, Bien and colleagues concluded from an analysis of three other studies that brief interventions enhanced the motivation of treatment-seeking problem drinkers to enter and remain in outpatient or residential alcohol treatment compared with clients not receiving such attention (Bien et al., 1993). Although other reviewers of brief interventions have reported more qualified reactions, all seem to agree that strong research evidence supports the use of brief interventions for heavy or excessive, nondependent drinkers, particularly those identified in general medical practice settings (Heather, 1995; Kahan et al., 1995; Mattick and Jarvis, 1994; Wilk et al., 1997). Wilk and colleagues examined evidence from 12 controlled clinical trials that randomized nearly 4,000 heavy drinkers to brief intervention or no intervention (Wilk et al., 1997). They concluded that heavy drinkers who received interventions in a primary care setting were almost twice as likely to moderate drinking than those who did not receive an intervention. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has also presented data on the efficacy and uses of brief interventions for dependent drinkers (NIAAA, 1999). This TIP reviews the most methodologically sound brief intervention studies and discusses methodological limitations of previous and current research in this area. The research is presented in two sections: (1) brief interventions for at-risk and problem use and (2) brief interventions for substance abuse. Brief Interventions for At-Risk And Problem UseA study conducted in 1983 focused on males in Malmo, Sweden, in the late 1970s (Kristenson et al., 1983). The subjects, advised to reduce their alcohol use in a series of health education visits, subsequently demonstrated significant reductions in gamma-glutamyl transferase levels and health care utilization up to 5 years after the brief interventions. The Medical Research Council (MRC) trial, conducted in 47 general practitioners' offices in Great Britain (Wallace et al., 1988), found significant reductions in alcohol use by the intervention group compared to the control group 12 months following the intervention. Anderson and Scott identified men and women from eight general practices in England who consumed more than 15 standard drinks (for men) or 9 standard drinks (for women) of alcohol per week (Anderson and Scott, 1992). These individuals were randomly assigned to receive either no intervention or feedback about the findings from the screening and 10 minutes of advice from the physician to reduce their consumption levels, accompanied by a pamphlet of self-help information. After 1 year, the males in the advice group had significantly reduced their mean weekly alcohol consumption by 2.8 ounces more than those who received no intervention. The females in both groups, however, showed significant reductions in alcohol consumption at the same followup point, with no between-group differences. In a widely publicized evaluation of brief interventions conducted in health care settings in 10 nations sponsored by WHO, the investigators identified 1,490 nonalcoholic heavy drinkers from eight core sites through a 20-minute health interview (Babor and Grant, 1991; Babor et al., 1994). These participants were randomly assigned to one of four groups: (1) no further intervention, (2) 5 minutes of simple advice about the importance of sensible drinking or abstinence, (3) simple advice plus 15 minutes of brief counseling and a self-help manual that encouraged the development of a habit-breaking-plan, or (4) at five of the sites, extended supportive counseling delivered in three extra sessions following the initial advice and 15-minute session. After 9 months, males who received any intervention, including the 5 minutes of advice, reported approximately 25 percent less daily alcohol consumption--a greater change than was observed in the no-intervention control group. Significantly, the men who showed the greatest response to simple advice had more severe alcohol problems and higher consumption patterns. Another interesting finding from the WHO study was that female participants in all groups had reduced their drinking at 9 months, regardless of whether they received any intervention. One explanation may be that the female participants were only recruited from two relatively affluent countries--Australia and the United States--thus, the results cannot be generalized to all women (Sanchez-Craig, 1994). Furthermore, the 20-minute comprehensive assessment was sufficiently intensive that some women may have responded to implicit messages of cutting down on consumption without further overt advice, especially considering that only 10 minutes of simple advice or 15 minutes of counseling were additionally provided (Kristenson and Osterling, 1994). One successful study demonstrated the efficacy of a brief alcohol intervention in a community-based primary care setting (Fleming et al., 1997). Project TrEAT (Trial for Early Alcohol Treatment) identified 723 men and women as problem drinkers from 17,695 patients who were screened in 17 community-based primary care practices. The outcomes studied were reductions in alcohol consumption and health resource utilization. In comparison with a no-intervention control group, the patients who received two 10- to 15-minute sessions of scripted advice (using a workbook that focused on advice, education, and contracting information) showed significantly greater reductions in alcohol consumption at a 12-month followup based on drinking levels during the previous week, episodes of binge drinking over the past month, and frequency of excessive drinking in the previous 7 days. Males in the study also had significantly fewer days of hospitalization than counterparts in the control group. Females in the experimental groups reduced their consumption significantly more than males in the experimental group. This research group (Fleming et al., 1999) also conducted a similar trial with primary care patients over 65 and found significant differences in drinking after 12 months for the experimental group compared to the control group. Miller and colleagues have developed a special form of a brief intervention known as the Drinker's Check-Up (Miller and Sovereign, 1989), designed to evaluate whether alcohol is harming an individual in any way. In the 1989 study, participants were recruited through media advertisements and were asked to come into a neutral setting for the assessment. As reported by Bien and colleagues, several trials of this approach have demonstrated encouraging results from providing systematic feedback about assessment results and some self-help options (Bien et al., 1993). Compared with a no-intervention group of respondents who had to wait 6 weeks for assessment, the recipients of immediate feedback and brief, empathic assistance showed prompt and persistent reductions (of 29 to 57 percent) in consumption patterns. More empathic counseling, an important component of brief interventions (see discussion on FRAMES earlier in this chapter), is also associated with larger reductions than the use of the more traditional confrontational styles (Miller et al., 1993). While the types of brief interventions vary, the basic design of most studies is a randomized controlled trial that assigns clients with hazardous drinking patterns either to a brief intervention (ranging from one to ten sessions) or to one or more control conditions (Anderson and Scott, 1992; Babor, 1992; Babor and Grant, 1991; Chick et al., 1985; Fleming et al., 1997; Harris and Miller, 1990; Heather et al., 1987; Kristenson et al., 1983; Persson and Magnusson, 1989; Wallace et al., 1988). Overall, the majority of brief alcohol intervention studies have found significantly greater improvements in drinking outcomes for the experimental group compared to the control group; however, most also found significant changes in drinking over time for both the control and brief intervention conditions. Meta-analyses found an effect size of 20 to 30 percent in studies conducted in health care settings (Bien et al., 1993; Kahan, 1985). Trials conducted since 1995 have garnered similar effect sizes with one trial finding a greater effect size for women (35 percent) (Fleming et al., 1997). Women were not always included in earlier trials, but later trials that did include women found that they were more likely than men to decrease their drinking based on brief targeted advice. Because of the success of brief alcohol interventions with adults in opportunistic settings, new trials with special populations (e.g., older adults, injured patients in emergency departments, pregnant women) are now being proposed and conducted. In addition, new technologies are being studied, including computerized real-time tailored booklets for at-risk drinkers, and the use of Interactive Voice Recognition (IVR) for interventions and followup. These and other technologies, if efficacious and effective, will provide clinicians with new tools to assist them in working with a difficult and important clinical and public health issue. Brief Interventions for Dependent UseMost studies of brief interventions for alcohol use that had the goal of changing drinking behavior have included only subjects who did not meet criteria for alcohol dependence and explicitly excluded dependent drinkers with significant withdrawal symptoms. The rationale for this practice was that alcohol-dependent individuals or those affected most severely by alcohol should be referred to formal specialized alcoholism treatment programs because their conditions are not likely to be affected by low intensity interventions (Babor et al, 1986; Institute of Medicine [IOM], 1990). However, there have been positive trials that address this issue specifically. NIAAA reviewed the studies focused on alcohol-dependent drinkers (NIAAA, 1999). Some of these studies focused on the effectiveness of motivating alcohol-dependent patients to enter specialized alcohol treatment. As long ago as 1962, a nonrandomized study was conducted of alcohol-dependent patients, identified in the emergency department (Chafetz et al., 1962). Of those receiving brief counseling, 65 percent followed through in keeping a subsequent appointment in a specialized alcohol treatment setting. Only 5 percent in the control group followed through with an appointment. Brief interventions have also been compared to more intensive and extensive treatment approaches used in traditional treatment settings with positive results (Edwards et al., 1977; Project MATCH Research Group, 1997, 1998). In a small study, the effectiveness of a one-session brief advice protocol plus monthly followup telephone calls, focused on the patient's personal responsibility to stop drinking, was compared to standard alcohol treatment for 100 men who were alcohol dependent (Edwards and Orford, 1977). At 1-year followup both groups reported a 40 percent decrease in alcohol-related problems. The study found, at 2-year followup, that the patients with the less severe alcohol problems did best in the brief intervention group. The patients with more serious alcohol-related problems did best in intensive alcohol treatment (Orford et al., 1976). Several similar studies conducted in New Zealand (Chapman and Huygens, 1988), London (Drummond et al., 1990), the United States (Miller et al., 1980, 1981; Miller and Munoz, 1982), and Norway (Skutle and Berg, 1987) essentially replicated the results of previous positive trials, comparing brief interventions favorably with a variety of extended treatments for problem drinking (including cognitive-behavior therapies, marital therapy, confrontational counseling, and standard inpatient and outpatient treatment). Sanchez-Craig and colleagues found that when comparing the 12-month treatment outcomes of severely dependent and nonseverely dependent men receiving brief treatment in Toronto and Brazil, there were no significant differences in "successful" outcomes as measured by rates of abstinence or moderate drinking (Sanchez-Craig et al., 1991). The IOM also noted that rates of spontaneous remission of alcoholism suggest that some portion of the most severe alcoholic population will reduce or discontinue their drinking without formal intervention (IOM, 1990). The largest multisite NIAAA-sponsored study of treatment matching and outcomes, Project MATCH (Matching Alcoholism Treatment to Client Heterogeneity), compared the effects of treatment type on outcomes for more than 1,500 alcohol-dependent patients (Project MATCH Research Group, 1997, 1998). Treatment types included (1) four 1-hour sessions of motivational enhancement therapy, which is often considered a brief intervention even though it is more intensive than most brief interventions (NIAAA, 1995), (2) 12 sessions of 12-Step facilitation, and (3) 12 sessions of cognitive-behavioral coping skills therapy. At 1- and 3-years postintervention, all three groups reported improvements including drinking less often and drinking fewer drinks per day. A small successful application of a brief motivational intervention within a substance abuse treatment setting administered approximately 1 hour of motivational interviewing for problem drinkers (adapted from Miller and Sovereign, 1989) to seriously opiate-dependent clients recently admitted to a methadone maintenance clinic (Saunders et al., 1995). Fifty-seven clients were randomized to the experimental group and were asked to identify positive and negative aspects of their opiate use and to project the consequences into the future. These clients were then asked to think about their use and discuss it at the 1-week followup session. The 65 subjects in the control group received a 1-hour educational intervention covering six substance-related issues such as overdose responses, legal aspects, and referral sources. Followup sessions were held with both groups at 1 week, 3 months, and 6 months. Significantly fewer clients receiving the motivational intervention dropped out of the study at each of the followup points compared with those receiving the educational component. By the 6-month point, the motivational subjects had significantly fewer opiate-related problems than the others. In comparison with the educational group, the clients receiving the motivational intervention were also more likely to make a positive initial shift on a stage-of-change measure (see the discussion of stages-of-change earlier in this chapter), express a stronger commitment to abstinence, remain in treatment longer, and relapse less quickly if they did drop out. The study concluded that brief motivational interventions strengthened recipients' resolution to abstain from opiate use and participate fully in treatment, and were therefore useful in improving performance and program compliance among clients attending a methadone clinic (Saunders, 1995). This and other studies have found that compliance with a treatment plan, rather than simply length of treatment, is one of the important factors influencing positive outcomes for clients receiving treatment. In a study looking at the costs of brief interventions, Holder and colleagues evaluated the evidence of clinical effectiveness and the typical costs of various alcoholism treatment modalities and found brief motivational counseling among the most effective in terms of a combination of clinical and cost effectiveness (Holder et al., 1991). It ranked third among the six highest ranking approaches in terms of weighted effectiveness (based on a total of nine studies conducted between 1983 and 1990). Brief motivational counseling was also rated the least costly of the six most effective modalities--or most cost-effective of 33 evaluated modalities. The authors of this study specifically stated that treatment planning and funding decisions should not be based on this initial effort to make "first level approximations" of cost-effectiveness. Critics have raised concerns that brief interventions could be construed as a treatment panacea for all patients with varying levels of alcohol-related problems and different consumption patterns (Drummond, 1997; Heather, 1995; Mattick and Jarvis, 1994). Although most researchers acknowledge that many clients do not need a protracted and expensive course of individual or group treatment, the literature advocating brief interventions as a treatment for all substance abuse is overstated (Heather, 1995; Mattick and Jarvis, 1994). Caution always needs to be employed in evaluating study recommendations. The clinical trials in this TIP on the use of brief interventions have been specific regarding the targeted population tested and the level of generalizability possible. Methodological IssuesIssues are frequently raised regarding specific methodological concerns of studies on brief interventions. First, many of the brief intervention studies, particularly those focused on alcohol, rely on self-report data to determine outcomes. The validity of measuring alcohol and other use by self-report is routinely questioned; however, reviewers of relevant literature have concluded that these data are generally valid and reliable (Midanik, 1982; Sobell and Sobell, 1990). Reports from collaterals, such as family members, are not as reliable except for highly visible events, such as drinking-related arrests (Midanik, 1982). Persons with hazardous drinking patterns will provide accurate information about their use, particularly under the following conditions: (1) the setting is a research or clinical one, (2) confidentiality is assured, and (3) the interview is administered when the respondent is sober (Sobell and Sobell, 1990). Techniques to increase the accuracy of self-reports have been employed in recent studies (Fleming et al., 1997, 1999). These studies use interviewers who fully understand drinking-related questions and can explain confusion about common terms (e.g., "blackouts," "high"). Concerns about the methodological limitations of some trials have included sample sizes that were too small and a statistical power insufficient to reliably detect differences between effects in the groups compared (Bien et al., 1993; Mattick and Jarvis, 1994). There may be differential attrition in groups at followup, and these dropouts can be ignored or excluded from analyses (Bien et al., 1993; Drummond, 1997; Kahan et al., 1995), or there could be contamination because the comparison group could be seeking additional treatment during the course of the research (Bien et al., 1993; Kahan et al., 1995; Mattick and Jarvis, 1994). Also, randomization of samples has not always been conducted (Wilk et al., 1997), and some early studies did not have control groups or did not have an adequate comparison group (Bien et al., 1993). Some of the newer brief intervention studies have addressed many of these concerns (Fleming et al., 1997, 1999). These, however, remain issues that must be addressed by new studies of brief intervention techniques with special populations and with new technology. Future Issues in Research and PracticeThe background research in this TIP is based on the most rigorous trials from the 1960s through the 1990s. As study designs have become more sophisticated, many of the earlier methodological issues are being addressed. Questions remain regarding specific levels of abuse and dependence after which brief intervention approaches are less effective and more intensive treatment is required. It is possible that factors such as social stability and support (as indicated in Edwards and Orford, 1977) play a role in improved responses to briefer treatments and that these factors may be more important than the level of substance abuse or dependence. As secondary analyses are conducted from more recent clinical trials, some of the strongest covariates will emerge. Further research focused specifically on the myriad of issues that could affect outcomes is needed to determine whether brief interventions can be useful for clients with dual diagnoses or whether they always require more intensive treatments because of the complexity of their illnesses. Although there is ongoing research testing the effectiveness of brief interventions with patients who have serious psychiatric illnesses and coexisting substance abuse disorders, there are no published studies that definitively address this issue. There is strong evidence supporting the efficacy of alcohol screening and brief interventions, in particular (Fleming et al., 1997). However, few studies to date have tested the implementation of brief intervention strategies in community-based medical and treatment settings. Several new initiatives address this critical next step in the process. Higgins-Biddle and colleagues identified the research base and current applications of screening and brief interventions (Higgins-Biddle et al., 1997). The findings on the effectiveness from clinical trials on screening and brief interventions were found to be encouraging, with risky drinkers reducing their alcohol consumption by 20 percent, on average. Individual study results varied from 15 to 40 percent depending on the population and methodology used. In the next few years, focused work in these areas will inform clinicians regarding optimal brief intervention implementation strategies and provide a bridge from research efficacy to practical application in real world clinical settings. There is evidence that a variety of brief interventions are effective with at-risk and hazardous substance users, and emerging evidence suggests that brief interventions can be used to motivate patients to seek specialized substance abuse treatment and to treat some alcohol-dependent persons. Clinical evidence also suggests that brief interventions can be used in specialized treatment programs to address specific targeted issues. In sum, the Consensus Panel believes it is critical for policymakers and providers of managed care to understand that brief interventions should never be thought of as the only treatment option for persons with substance abuse problems but as one of a continuum of techniques for use with a population of clients with substance abuse problems ranging from at-risk to dependent use. |
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